February 23, 2007HeartOpen Access

Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels: Figure 1

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Why the study?

Are increased uric acid levels associated with worsening haemodynamic compromise in patients with heart failure independent of BNP?

Population

106 patients with heart failure referred for right heart catheterisation between 1 January 2003 and 1 July…

Comparison

High serum uric acid levels (above median) vs Low serum uric acid levels (below median)

Design

Cross-sectional

Authors

MKM. KittlesonHeart Failure & Transplant MJMarcus E. St. JohnBaptist Hospital of Miami VBValeriani R. BeadJohns Hopkins University

Discussion

Member takes

Implication

Uric acid may mark haemodynamic compromise beyond NT-proBNP in HF; hypothesis-generating, needs prospective validation before any clinical role.

Structured PICO

Are increased uric acid levels associated with worsening haemodynamic compromise in patients with heart failure independent of BNP?

Population

106 patients with heart failure referred for right heart catheterisation between 1 January 2003 and 1 July 2004. Excluded: heart transplant recipients or patients currently receiving synthetic human BNP.

Intervention

High serum uric acid levels (above median)

Comparator

Low serum uric acid levels (below median)

Outcome

Haemodynamic parameters (right atrial, pulmonary arterial, and pulmonary capillary wedge pressures, and cardiac output) measured during right heart catheterisationsurrogate

This study investigates whether uric acid levels can predict haemodynamic compromise in heart failure patients independently of NT-proBNP.

Cite This Study

Kittleson et al. (2007) studied this question.

synapsesocial.com/papers/6a71f8e51556b380a2273e95 https://doi.org/10.1136/hrt.2006.090845

Topics

HFrEF treatment Heart failure

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Implication

Uric acid may mark haemodynamic compromise beyond NT-proBNP in HF; hypothesis-generating, needs prospective validation before any clinical role.

Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels: Figure 1

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels: Figure 1

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider