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January 1, 1988Journal of HepatologyOpen Access

Plasma catecholamine level and portal venous pressure as guides to prognosis in patients with cirrhosis

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Why the study?

Do plasma catecholamine levels and portal venous pressure predict survival in patients with alcoholic cirrhosis?

Population

81 patients with alcoholic cirrhosis

Design

Cohort

Follow-up

up to 8 years

Authors

UTUlrik Tage‐JensenStatens Serum InstitutJHJens H. HenriksenStatens Serum InstitutECErik ChristensenMaine Medical Center

Discussion

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Implication

May refine prognostication in alcoholic cirrhosis; hypothesis-generating and requires prospective validation before clinical use.

Structured PICO

Do plasma catecholamine levels and portal venous pressure predict survival in patients with alcoholic cirrhosis?

P
Population
81 patients with alcoholic cirrhosis
I
Intervention
Measurement of plasma catecholamine levels (noradrenaline, adrenaline) and portal venous pressure
O
Outcome
Survival (mortality)hard clinical

Plasma noradrenaline and portal pressure are independent predictors of survival in patients with alcoholic cirrhosis, suggesting sympathetic nervous system activity indicates disease severity.

Cite This Study

Tage‐Jensen et al. (1988) studied this question.

synapsesocial.com/papers/6a71fb0b87f92105712869e2https://doi.org/10.1016/s0168-8278(88)80053-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure1984 · 3,142 citations
  2. 2Enhanced sympathetic nervous activity after intravenous propranolol in ischaemic heart disease: plasma noradrenaline splanchnic blood flow and mixed venous oxygen saturation at rest and during exercise1978 · 71 citations
  3. 3Determination of the Hepatic Galactose Elimination Capacity after a Single Intravenous Injection in Man: The reproducibility and the influence of uneven distribution1963 · 123 citations
  4. 4Norepinephrine: hormone and neurotransmitter in man.1978 · 338 citations
  5. 5Multivariate survival analysis using Cox's regression model1987 · 381 citations