Why the study?
Do oxprenolol and practolol reduce blood pressure in patients with hypertension?
Do oxprenolol and practolol reduce blood pressure in patients with hypertension?
Oxprenolol and practolol significantly reduce blood pressure in hypertensive patients, but achieve clinically adequate control in a minority of cases.
May support modest BP lowering with these agents but not monotherapy in most patients; leaves open their role versus contemporary regimens.
In controlled trials of the beta-adrenergic blocking drugs oxprenolol and practolol in hypertension both drugs were well tolerated without side effects and caused statistically significant non-postural reduction of blood pressure. In less than half the patients on eitherdrug the reduction of blood pressure was clinically adequate. No attempt was made to compare the two drugs.
No takes yet. Share an insight, caveat, or question.
Leishman et al. (1970) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: