Intracellular injection of cAMP or cGMP causes membrane depolarization and increased conductance in rat sympathetic ganglion cells, suggesting they do not mediate the slow inhibitory postsynaptic potential via hyperpolarization.
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Does not support cAMP/cGMP mediation of slow IPSP via hyperpolarization; leaves open ganglionic inhibitory mechanisms for further study.
Gallagher et al. (1977) studied this question.
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