Why the study?
Does halofantrine inhibit HERG potassium channels in CHO-K1 cells?
Does halofantrine inhibit HERG potassium channels in CHO-K1 cells?
Halofantrine inhibits HERG potassium channels, providing a cellular mechanism for its clinical association with QT prolongation and torsades de pointes.
No takes yet. Share an insight, caveat, or question.
Supports halofantrine QT risk mechanism; leaves open clinical translation from cellular data.
Tie et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: