Abortion in sows experimentally infected with African swine fever virus: Pathogenesis studies

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Population

13 sows that were 38 to 92 days pregnant

Design

Preclinical

Authors

Discussion

Maternal tissue sampling may improve ASF abortion diagnosis in sows; leaves open broader applicability and mechanisms in other models.

Population

13 sows that were 38 to 92 days pregnant

Intervention

Experimental infection with an African swine fever (ASF) virus strain of low virulence (Dominican Republic isolate)

Outcome

Pathogenesis of abortions evaluated using virus isolation, tissue immunofluorescence, and histopathologic techniques

Specific diagnosis of abortion resulting from ASF infection should be based on examination of maternal tissues rather than fetal tissues.

Schlafer et al. (1987) studied this question.

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