Why the study?
Does synthetic ANP infusion improve hemodynamic and humoral variables in patients with severe congestive heart failure?
Population
8 patients, aged 26 to 71 years, with severe congestive heart failure due to ischemic heart disease or…
Design
Case_series
Follow-up
up to 3 hours
Authors
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May support ANP in severe HF; hypothesis-generating and should not yet change practice.
Does synthetic ANP infusion improve hemodynamic and humoral variables in patients with severe congestive heart failure?
Low-dose infusion of synthetic ANP in severe heart failure patients significantly reduces pulmonary capillary wedge pressure and plasma epinephrine levels, though it may cause hypotension in some patients.
Goy et al. (1988) studied this question.
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