Why the study?
Cardiovascular reactivity to the cold pressor test is considered a marker for apparent and potential hypertension, but the association between changes in carotid arterial wave intensity during the test and hypertension was unclear.
Does the cold pressor test elicit different changes in carotid arterial wave intensity in hypertensive versus normotensive subjects?
Does the cold pressor test elicit different changes in carotid arterial wave intensity in hypertensive versus normotensive subjects?
The direction of change in carotid wave intensity during the cold pressor test provides an objective, non-subjective marker to discriminate cardiovascular reactivity between hypertensive and normotensive individuals.
Answers are grounded in this paper and cite their sources.
WI response to CPT differs by hypertension status; hypothesis-generating for ventriculo-arterial assessment and needs prospective validation.
Purpose Cardiovascular reactivity to the cold pressor test (CPT) is considered to be a marker for apparent and potential hypertension. We aimed to elucidate the association between the changes in wave intensity (WI) during CPT and hypertension. Methods We recruited 85 volunteers, 33 of whom were hypertensive and 52 normotensive. Using ultrasonic equipment during CPT, we measured carotid arterial WI, which is defined in terms of blood pressure and velocity in the carotid artery. Results The peak WI (W 1 ) increased during CPT in 70.6% of hypertensive individuals, but decreased in 72.6% of normotensive individuals. The chi-square (χ 2 ) test showed that the association between the direction of change in W 1 (increase or decrease) and the blood pressure (hypertensive or normotensive) was very strong ( P < 0.0001). Conclusion Direction of change in W 1 during CPT is a clear marker to discriminate cardiovascular reactivity that does not vary depending on each investigator’s subjective point of view.
No takes yet. Share an insight, caveat, or question.
Tanaka et al. (2021) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: