Why the study?
Does streptokinase reduce the size and extent of thrombosis compared to anticoagulants in patients with deep vein thrombosis?
Population
10 patients with deep vein thrombosis
Comparison
Streptokinase vs Anticoagulants
Design
Cohort
Follow-up
7-10 days
Authors
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May reduce DVT thrombus size; small observational data leave open need for RCTs before practice change.
Does streptokinase reduce the size and extent of thrombosis compared to anticoagulants in patients with deep vein thrombosis?
Streptokinase can lyse fresh thrombus surrounded by flowing blood in patients with deep vein thrombosis, leading to a reduction in thrombus size compared to standard anticoagulants.
Browse et al. (1968) studied this question.
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