A new, genetically distinct GII.17 norovirus variant emerged and became the predominant cause of acute gastroenteritis outbreaks in Jiangsu, China, between late 2014 and early 2015.
GII.17 variant drove most outbreaks; leaves open questions on global spread and vaccine impact.
From September 2014 to March 2015, 23 outbreaks of norovirus (NoV) acute gastroenteritis occurred in Jiangsu, China. Partial sequencing of the NoV capsid gene suggested that 16 of the 23 outbreaks were related to a new GII.17 variant. This variant was first detected in sporadic specimens in October 2014, and became predominant in February 2015. Analysis of the RNA-dependent RNA polymerase (RdRp), and complete capsid including the protruding domain P2 sequences confirmed this GII.17 variant as distinct from previously identified GII variants.
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Fu et al. (2015) studied this question.
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