Key result
Novel norovirus GII.17 replaces GII.4 in Shanghai, driving ~64% of GII infections.
Absolute Event Rate: 63.84% vs 29.69%
The novel norovirus genotype GII.17 emerged and replaced GII.4 as the predominant strain causing acute gastroenteritis in Shanghai in 2014-2015.
In the winter of 2014-2015, a novel norovirus (NoV) strain (GII.17) was reported to be the major cause of gastroenteritis outbreaks in East Asia. To determine the time course of gastroenteritis infections associated with the GII.17 strain and whether GII.17 was the main epidemic strain in diarrheal patients in Shanghai, 2169 stool samples were collected and tested. The detection rate of NoV GI and GII NoV strains was 0.83 and 24.02%, respectively. Phylogenetic analysis confirmed that there were seven NoV genotypes, among which GII.4 and GII.17 were the main genotypes. The GII.17 strain was first detected in a sample collected on August 14th, 2014, and beginning in January 2015, the novel GII.17 strain replaced the GII.4 strain as the dominant NoV genotype causing acute gastroenteritis in patients in Shanghai.
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Pan et al. (2016) conducted a letter in Acute gastroenteritis (n=2,169). Norovirus genotype GII.17 vs. Norovirus genotype GII.4 was evaluated on Prevalence among NoV GII positive samples (July 2014 to January 2015). The novel norovirus genotype GII.17 emerged as the predominant strain in Shanghai, replacing GII.4 and accounting for 63.84% of GII infections between July 2014 and January 2015.
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