August 13, 2018BMC NephrologyOpen Access

Among 482 patients with diabetes, 174 (42.9%) had eGFR < 60 ml/min, of which 43 (24.7%) were normoalbuminuric, representing 10.8% of the total sample.

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Population

482 adult patients with diabetes attending medical clinics at a teaching hospital in Sri Lanka. Mean age…

Design

Cross-sectional

Authors

PLPolwatta Liyanage Gayani Chandima Liyanage SLSarath Lekamwasam TWThilak Priyantha Weerarathna

Discussion

Member takes

Overview

Normoalbuminuric low-GFR diabetes warrants clinical attention; leaves open optimal screening and progression risk in prospective studies.

Structured PICO

Population

482 adult patients (>20 years) with diabetes attending medical clinics at a teaching hospital in Sri Lanka. Mean age 60.7 years, 75.1% female. Excluded: pregnant/lactating, acute/chronic infections, non-diabetic renal disease, symptomatic heart failure.

Outcome

Prevalence of normoalbuminuric renal insufficiency (eGFR < 60 ml/min/1.73m2 with normoalbuminuria)surrogate

A significant proportion of diabetic patients develop renal insufficiency without preceding albuminuria, suggesting microalbuminuria alone is insufficient for diabetic nephropathy screening.

Limitations

Hospital-based sample
Older patient population with longer disease duration compared to other studies
High background prevalence of chronic kidney disease of unknown origin (CKDu) in the region

Cite This Study

Liyanage et al. (2018) studied this question.

synapsesocial.com/papers/6a722f6e87f9210571287c9d https://doi.org/10.1186/s12882-018-1001-7

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August 13, 2018BMC NephrologyOpen Access

Among 482 patients with diabetes, 174 (42.9%) had eGFR < 60 ml/min, of which 43 (24.7%) were normoalbuminuric, representing 10.8% of the total sample.

View Full Paper

Ask AI

Bookmark

Population

482 adult patients with diabetes attending medical clinics at a teaching hospital in Sri Lanka. Mean age…

Design

Cross-sectional

Authors

PLPolwatta Liyanage Gayani Chandima Liyanage SLSarath Lekamwasam TWThilak Priyantha Weerarathna

Discussion

Member takes

Overview

Normoalbuminuric low-GFR diabetes warrants clinical attention; leaves open optimal screening and progression risk in prospective studies.

Structured PICO

Population

Outcome

Prevalence of normoalbuminuric renal insufficiency (eGFR < 60 ml/min/1.73m2 with normoalbuminuria)surrogate

A significant proportion of diabetic patients develop renal insufficiency without preceding albuminuria, suggesting microalbuminuria alone is insufficient for diabetic nephropathy screening.

Limitations

Hospital-based sample
Older patient population with longer disease duration compared to other studies
High background prevalence of chronic kidney disease of unknown origin (CKDu) in the region

Cite This Study

Liyanage et al. (2018) studied this question.

synapsesocial.com/papers/6a722f6e87f9210571287c9d https://doi.org/10.1186/s12882-018-1001-7

Also Consider

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