Key result
Reduced GFR (<90 ml/min/1.73 m2) was present in 23 of 105 normoalbuminuric type 1 diabetic patients and was associated with more advanced diabetic glomerular lesions.
Population
105 normoalbuminuric type 1 diabetic patients with at least 10 years of diabetes duration who had a renal…
Design
Cross-sectional
Authors
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Reduced GFR may signal advanced lesions in normoalbuminuric T1D; observational data leave open whether monitoring changes outcomes.
Cross-Sectional (n=105)
Reduced GFR can occur in long-standing normoalbuminuric type 1 diabetic patients and is associated with advanced diabetic glomerular lesions, suggesting a need for regular GFR monitoring especially in females with retinopathy or hypertension.
Caramori et al. (2003) conducted a cross-sectional in Normoalbuminuric type 1 diabetes (n=105). Reduced GFR (<90 ml x min(-1) x 1.73 m(-2)) vs. Normal GFR (>/=90 ml x min(-1) x 1.73 m(-2)) was evaluated on Advanced diabetic glomerular lesions. Reduced GFR (<90 ml/min/1.73 m2) was present in 23 of 105 normoalbuminuric type 1 diabetic patients and was associated with more advanced diabetic glomerular lesions.
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