Key result
In normoalbuminuric normotensive type 1 diabetic patients, GFR significantly decreased from 137.6 to 116.4 ml/min/1.73 m2 (P<0.05) and mean blood pressure increased over an 8.4-year follow-up.
Population
33 normotensive normoalbuminuric (24-h UAER <20 microg/min) type 1 diabetic patients
Design
Cohort
Follow-up
8.4+/-2.1 years
Authors
Loading...
Long-term cohort data in normoalbuminuric type 1 diabetes warrant vigilant renal monitoring; leaves open whether early intervention prevents progression.
Cohort (n=33)
Absolute Event Rate: 116.4% vs 137.6%
p-value: p=< 0.05
In normotensive, normoalbuminuric type 1 diabetic patients, GFR decreases and blood pressure increases over an 8-year period, with baseline GFR predicting both changes.
Caramori et al. (1999) conducted a cohort in Type 1 diabetes (n=33). Type 1 diabetes vs. Baseline was evaluated on Glomerular filtration rate (GFR) (p=< 0.05). In normoalbuminuric normotensive type 1 diabetic patients, GFR significantly decreased from 137.6 to 116.4 ml/min/1.73 m2 (P<0.05) and mean blood pressure increased over an 8.4-year follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: