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June 22, 2011European Journal of Preventive CardiologyOpen Access

Common carotid intima-media thickness in cardiovascular risk stratification of older people: the Rotterdam Study

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Why the study?

Does the addition of common carotid intima-media thickness to traditional risk factors improve cardiovascular risk classification in older people?

Population

3,580 non-diabetic people aged 55-75 years and free of cardiovascular disease at baseline

Comparison

Common carotid intima-media thickness… vs Framingham risk factors alone

Design

Cohort

Follow-up

median 12.2 years

Authors

SESuzette Elias‐SmaleRadboud University Nijmegen
Maryam Kavousi
Maryam KavousiGeneral / Preventive / Lipids
GVGermaine C. VerwoertGoethe University Frankfurt

Discussion

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Member takes

Overview

Should not yet change risk stratification in older adults; leaves open incremental value of cIMT in women.

Structured PICO

Does the addition of common carotid intima-media thickness to traditional risk factors improve cardiovascular risk classification in older people?

P
Population
3,580 non-diabetic people aged 55-75 years and free of cardiovascular disease at baseline
I
Intervention
Common carotid intima-media thickness (cIMT) measurement added to Framingham risk factors
C
Comparator
Framingham risk factors alone
O
Outcome
10-year risk classification of hard coronary heart disease (CHD) and stroke

Adding common carotid intima-media thickness to traditional risk factors modestly improves cardiovascular risk stratification in older women, but not in older men.

Cite This Study

Elias‐Smale et al. (2011) studied this question.

synapsesocial.com/papers/6a724545f44fa9f079dfcea6https://doi.org/10.1177/1741826711414623
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)2001 · 26,200 citations
  2. 2Is Carotid Intima-Media Thickness Useful in Cardiovascular Disease Risk Assessment?2001 · 246 citations
  3. 3Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness2007 · 2,977 citations
  4. 4Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study.1994 · 717 citations