Why the study?
Does monocrotaline-induced pulmonary hypertension alter linear and non-linear heart rate dynamics in adult Wistar rats?
Does monocrotaline-induced pulmonary hypertension alter linear and non-linear heart rate dynamics in adult Wistar rats?
Monocrotaline-induced pulmonary hypertension in rats leads to short-term increases in sympathetic activity and long-term changes in heart rate dynamics compared to vehicle-treated controls.
MCT rat model links PH to altered HR dynamics; leaves open translation to human autonomic monitoring or therapy.
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Gonçalves et al. (2010) studied this question.
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