What question did this study set out to answer?

To assess whether fasting insulin regulates current blood pressure and predicts future blood pressure changes in healthy children and adolescents over a six-year period.

March 1, 1996American Journal of HypertensionOpen Access

Insulin and blood pressure among healthy children Cardiovascular risk in young finns

View Full Paper

Ask AI

Bookmark

Why the study?

Does fasting serum insulin predict future blood pressure in healthy children and adolescents?

Population

3,596 to 2,799 healthy Finnish children and adolescents aged 3 to 18 years

Design

Cohort

Follow-up

6 years

Authors

LTLeena TaittonenPediatric Cardiology

Discussion

Member takes

Implication

May indicate insulin as early BP predictor in youth; extends cross-sectional links longitudinally but remains hypothesis-generating without practice implications.

Key Points

To assess whether fasting insulin regulates current blood pressure and predicts future blood pressure changes in healthy children and adolescents over a six-year period.
Followed 2,799 to 3,596 Finnish children and adolescents aged 3 to 18 years across three triennial surveys conducted between 1980 and 1986.
Measured height, weight, systolic blood pressure, diastolic blood pressure (Korotkoff phase 5), and fasting serum insulin at each survey.
Evaluated relationships using age-group stratifications, bivariate correlations, partial correlations adjusting for age and weight, and multiple regression models.
Fasting insulin correlated positively with concurrent systolic and diastolic blood pressure across all age groups (correlation coefficients r = 0.10 to 0.41; partial r = 0.02 to 0.15).
Baseline insulin predicted systolic blood pressure (r = 0.30 to 0.47; partial r = 0.06 to 0.13) and diastolic blood pressure (r = 0.17 to 0.35; partial r = 0.05 to 0.08) at 3 and 6 years of follow-up.
Correlations between baseline insulin and longitudinal blood pressure change, as well as between changes in insulin and changes in blood pressure, were statistically non-significant or marginal.

Structured PICO

Does fasting serum insulin predict future blood pressure in healthy children and adolescents?

Population

3,596 to 2,799 healthy Finnish children and adolescents aged 3 to 18 years

Intervention

Fasting serum insulin levels (exposure)

Outcome

Systolic and diastolic blood pressure measured concurrently and 3 to 6 years latersurrogate

Fasting insulin levels positively correlate with and predict future systolic and diastolic blood pressure in children and adolescents, independent of age and weight.

Cite This Study

Leena Taittonen (1996) studied this question.

synapsesocial.com/papers/6a724fe9c1a24a6142dbd449 https://doi.org/10.1016/0895-7061(95)00345-2

View Full Paper

Ask AI

Bookmark

Implication

May indicate insulin as early BP predictor in youth; extends cross-sectional links longitudinally but remains hypothesis-generating without practice implications.

Insulin and blood pressure among healthy children Cardiovascular risk in young finns

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Insulin and blood pressure among healthy children Cardiovascular risk in young finns

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider