June 10, 2013Journal of Cardiovascular Electrophysiology
Fragmented QRS Complex Predicts the Arrhythmic Events in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia
Why the study?
Does the presence of fragmented QRS complex on ECG predict arrhythmic events in patients with ARVC/D?
Population
78 patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia according to 2010 modified Task…
Comparison
Presence of fragmented QRS complex on standard… vs Absence of fragmented QRS (frQRS) complex
Design
Cohort
Follow-up
38 ± 14 months
Authors
Discussion
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Member takes
Implication
frQRS may identify higher arrhythmic risk in ARVC/D; hypothesis-generating and requires prospective validation before clinical use.
Structured PICO
Does the presence of fragmented QRS complex on ECG predict arrhythmic events in patients with ARVC/D?
P
Population
78 patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) according to 2010 modified Task Force Criteria, mean age 31.25 ± 11.5 years, 65.4% men. Patients with complete/incomplete right bundle branch block were excluded.
I
Intervention
Presence of fragmented QRS (frQRS) complex on standard 12-lead ECG
C
Comparator
Absence of fragmented QRS (frQRS) complex
O
Outcome
Arrhythmic events (sudden death, ventricular tachycardia, and ventricular fibrillation)hard clinical
The presence and extent of fragmented QRS on a standard 12-lead ECG can serve as a significant predictor of fatal and nonfatal arrhythmic events in patients with ARVC/D.
Limitations
- Retrospective design
- Need for large scale and prospective studies to confirm findings
Cite This Study
Canpolat et al. (2013) studied this question.