Why the study?
Angiotensinogen and aldosterone regulate blood pressure and are implicated in cardiovascular disease pathogenesis, but the role of DNA methylation in regulating AGT and CYP11B2 requires clarification.
Design
Review
Authors
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May inform epigenetic hypertension mechanisms; hypothesis-generating and should not yet change practice.
Key points are not available for this paper at this time.
Takeda et al. (2021) studied this question.
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