Key result
Intrarenal RAAS is independently regulated, and urinary angiotensinogen serves as a useful biomarker for identifying the status of intrarenal RAAS, hypertension, and renal disease.
Design
Review
Authors
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May support urinary angiotensinogen for intrarenal RAAS assessment in hypertension and renal disease; leaves open prospective validation before clinical use.
This review highlights the independent regulation of the intrarenal RAAS and the potential utility of urinary angiotensinogen as a biomarker for intrarenal Ang II generation in the context of hypertension and renal disease.
Nishiyama et al. (2018) conducted a review in Hypertension and renal disease. Urinary angiotensinogen was evaluated. Intrarenal RAAS is independently regulated, and urinary angiotensinogen serves as a useful biomarker for identifying the status of intrarenal RAAS, hypertension, and renal disease.
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