May 1, 2000Pediatric Anesthesia

Fenoldopam for controlled hypotension during spinal fusion in children and adolescents

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Why the study?

Does fenoldopam safely induce controlled hypotension during spinal fusion in children and adolescents?

Population

10 children and adolescents, aged 8-14 years and weighing 22-61 kg, undergoing anterior or posterior spinal…

Design

Case_series

Follow-up

Intraoperative (135-225 min)

Authors

JTJoseph D. TobiasArkansas Children's Hospital

Discussion

Member takes

Implication

Hypothesis-generating for fenoldopam in pediatric controlled hypotension; prospective trials needed before clinical adoption.

Structured PICO

Does fenoldopam safely induce controlled hypotension during spinal fusion in children and adolescents?

Population

10 children and adolescents, aged 8-14 years and weighing 22-61 kg, undergoing anterior or posterior spinal fusion

Intervention

Fenoldopam infusion (starting dose 0.3-0.5 microg/kg/min, increased incrementally to achieve MAP 50-65 mmHg) administered for 135-225 min

Outcome

Achievement of mean arterial pressure (MAP) of 50-65 mmHgsurrogate

Fenoldopam can effectively and safely provide controlled hypotension during spinal surgery in children and adolescents.

Limitations

Lack of direct comparison to other commonly used agents
Unknown effects on estimated blood loss

Cite This Study

Joseph D. Tobias (2000) studied this question.

synapsesocial.com/papers/6a7255fbfebe604dd70a8cb6 https://doi.org/10.1046/j.1460-9592.2000.00502.x

View Full Paper

Ask AI

Bookmark

Fenoldopam for controlled hypotension during spinal fusion in children and adolescents

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Fenoldopam for controlled hypotension during spinal fusion in children and adolescents

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider