Why the study?
Does intravenous fenoldopam alter renal and systemic hemodynamics in healthy male subjects?
Population
18 healthy male subjects
Comparison
Fenoldopam administered intravenously in doses… vs Different doses of fenoldopam in a three-way…
Design
Other
Follow-up
2 hours
Authors
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Supports further trials in renally impaired patients; extends dose-response data on DA-1 agonism to human hemodynamics.
Does intravenous fenoldopam alter renal and systemic hemodynamics in healthy male subjects?
Intravenous fenoldopam causes systemic arteriolar vasodilation and renal vasodilation with increased sodium excretion in healthy subjects.
Allison et al. (1987) studied this question.
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