Why the study?
Does intravenous fenoldopam reduce blood pressure and improve renal hemodynamics in patients with essential hypertension?
Population
17 patients with essential hypertension (mean blood pressure 152/101 mm Hg)
Design
Cohort
Follow-up
2 hours
Authors
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Fenoldopam was associated with renal hemodynamic gains and BP reduction; hypothesis-generating and should not yet change practice.
Does intravenous fenoldopam reduce blood pressure and improve renal hemodynamics in patients with essential hypertension?
Intravenous fenoldopam effectively reduces blood pressure while simultaneously enhancing renal plasma flow and sodium excretion in patients with essential hypertension.
Murphy et al. (1987) studied this question.
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