May 1, 1997HeartOpen Access

Left atrial appendage function during DDD and VVI pacing.

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Why the study?

Does DDD pacing improve left atrial appendage function compared to VVI pacing in patients with dual chamber pacemakers?

Structured PICO

Does DDD pacing improve left atrial appendage function compared to VVI pacing in patients with dual chamber pacemakers?

Population

22 patients (mean age 68 (SD 6) years) with a normal atrium who had been paced with dual chamber pacemakers for at least six months. Exclusion criteria: valvar disease, cardiomyopathy, hypertension, and diabetes mellitus.

Intervention

DDD pacing mode for at least two months

Comparator

VVI pacing mode for at least two months

Outcome

Echocardiographic indices of left atrial appendage flow (emptying and filling flow velocities and integrals)surrogate

DDD pacing results in significantly better left atrial appendage emptying and filling compared to VVI pacing, potentially explaining the lower thromboembolic risk associated with dual-chamber pacing.

Discussion

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Implication

Supports DDD over VVI for left atrial appendage function; extends mechanistic basis for lower thromboembolic risk with dual-chamber pacing.

Cite This Study

Simantirakis et al. (1997) studied this question.

synapsesocial.com/papers/6a7258b9f44fa9f079dfddf2 https://doi.org/10.1136/hrt.77.5.428

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Implication

Supports DDD over VVI for left atrial appendage function; extends mechanistic basis for lower thromboembolic risk with dual-chamber pacing.

Left atrial appendage function during DDD and VVI pacing.

Structured PICO

Discussion

Implication

Cite This Study

Left atrial appendage function during DDD and VVI pacing.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider