Why the study?
Does hydrochlorothiazide cause acute pulmonary edema?
Does hydrochlorothiazide cause acute pulmonary edema?
Hydrochlorothiazide-induced pulmonary edema is a rare but potentially life-threatening idiosyncratic reaction that should be considered in the differential diagnosis of pulmonary edema.
Answers are grounded in this paper and cite their sources.
Hydrochlorothiazide may rarely trigger acute pulmonary edema; this case report leaves open questions of incidence and causality.
A 46-year-old woman had features of acute pulmonary edema soon after taking hydrochlorothiazide (HCTZ) for the first time. Although 31 cases of HCTZ-induced pulmonary edema have been reported in the world literature since it was first described in 1968, little is known about this clinical entity. Because its presence may be underestimated or underreported, it must be considered in the differential diagnosis in any case of pulmonary edema in a patient taking HCTZ. It is important to review the pathophysiology and management of this rare but potentially life-threatening idiosyncratic reaction to a commonly prescribed drug.
No takes yet. Share an insight, caveat, or question.
Khalid F. Almoosa (1999) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: