Population
Single skeletal muscle channels incorporated into bilayers or macropatches of Xenopus laevis oocytes…
Comparison
Exposure of the intracellular side to HO vs Extracellular exposure to H(2)O(2) or baseline
Design
Preclinical
Authors
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ROS may modulate vascular BKCa function under oxidative stress; hypothesis-generating and leaves open relevance in intact systems.
Intracellular reactive oxygen species inhibit large-conductance Ca2+-activated K+ channels by decreasing open probability via hydroxyl radical-mediated modification.
Soto‐Arriaza et al. (2002) studied this question.
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