Why the study?
Despite progress, important questions remain regarding the ontogenetic basis, phenotypic diversity, and signaling mechanisms underlying bicuspid aortic valve-associated aortopathy.
Design
Review
Authors
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Key BAV aortopathy questions remain unresolved; leaves open mechanistic and prognostic research before clinical translation.
This review highlights the current understanding and critical knowledge gaps in bicuspid aortic valve-associated aortopathy, emphasizing the need for collaborative research.
Meßner et al. (2019) studied this question.
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