Why the study?
Does provirus load correlate with antibody titer in HTLV-I carriers?
Population
1015 Okinawan high school students, including 17 identified HTLV-I carriers
Design
Cross-sectional
Authors
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Antibody testing may miss low-load HTLV-I carriers; hypothesis-generating for PCR-augmented screening in endemic settings.
Does provirus load correlate with antibody titer in HTLV-I carriers?
A small percentage of HTLV-I carriers may be seronegative because antibody titers strongly correlate with provirus load, falling below detection limits in those with low viral loads.
Miyata et al. (1995) studied this question.
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