Why the study?
Does metabolic syndrome with CAD alter the gene expression of adiponectin, TNF-α, and leptin in adipose tissues compared to patients without MS and CAD?
Does metabolic syndrome with CAD alter the gene expression of adiponectin, TNF-α, and leptin in adipose tissues compared to patients without MS and CAD?
Metabolic syndrome with CAD is associated with adverse alterations in adipocytokine gene expression in cardiac and subcutaneous adipose tissues, suggesting a role in disease pathogenesis.
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May link MS-CAD to adverse adipocytokine shifts; hypothesis-generating and requires prospective validation before clinical implications.
Görmez et al. (2011) studied this question.
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