Why the study?
Does acute hyperlipidemia induced by Intralipid infusion impair baroreflex control or increase sympathetic nerve activity in young adults?
Population
18 young adults
Comparison
Infusion of Intralipid (0.8 ml x m x min) and… vs Infusion of saline (0.8 ml x m x min) and heparin
Design
RCT, randomized, double-blinded, placebo-controlled
Follow-up
60 min
Authors
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Acute hyperlipidemia does not impair baroreflex sensitivity in young adults; extends evidence that acute lipid effects on autonomic function may require chronic exposure or comorbidities.
Does acute hyperlipidemia induced by Intralipid infusion impair baroreflex control or increase sympathetic nerve activity in young adults?
Acute hyperlipidemia does not appear to impair reflex cardiovagal or sympathetic regulation in healthy young adults.
Monahan et al. (2007) studied this question.
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