The study proposes a mathematical model and electronic-integration modification to improve the speed and accuracy of estimating cardiac output and central circulating blood volume from dilution curves.
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Proposed formulas for cardiac output from dilution curves should not yet change practice; leaves open prospective validation of accuracy.
The graphical method of estimating cardiac output and central circulating blood volume is reviewed. An electronic-integration modification is described for fast, accurate cardiacoutput estimation. A mathematical representation of biphasic dilution curves is developed and, based on this analysis, formulas are proposed for determination of cardiac output and central circulating blood volume. Clinical application of this determination method is shown, and its advantages are discussed.
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Gott et al. (1961) studied this question.
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