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April 1, 1999Arteriosclerosis Thrombosis and Vascular BiologyOpen Access

Structural, Functional, and Hemodynamic Changes of the Common Carotid Artery With Age in Male Subjects

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Population

69 male subjects between the ages of 16 and 75, screened for the absence of major atherosclerotic risk…

Design

Cross-sectional

Authors

ASArno Schmidt‐TrucksässPreventive CardiologyDGDominik GrathwohlNestlé (Switzerland)ASAndreas SchmidUniversity of Bayreuth

Discussion

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Implication

Age-related carotid changes in healthy males should not yet alter practice; hypothesis-generating and requires longitudinal confirmation of prognostic value.

Structured PICO

P
Population
69 male subjects between the ages of 16 and 75 (mean age 42.4+/-16.5 years), screened for the absence of major atherosclerotic risk factors or existing vascular disease.
O
Outcome
Age-related multiparametric changes of the common carotid artery (CCA) properties assessed with ultrasoundsurrogate

Aging in healthy males is associated with significant, nearly linear increases in carotid intima-media thickness and diastolic diameter, alongside decreases in peak expansion and blood flow velocities.

Cite This Study

Schmidt‐Trucksäss et al. (1999) studied this question.

synapsesocial.com/papers/6a726d79febe604dd70a985fhttps://doi.org/10.1161/01.atv.19.4.1091
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Relation of Intima-Media Thickness to Atherosclerotic Plaques in Carotid Arteries1996 · 271 citations
  2. 2Arterial enlargement in the atherosclerosis risk in communities (ARIC) cohort. In vivo quantification of carotid arterial enlargement. The ARIC Investigators.1994 · 138 citations
  3. 3Association Between Intima-Media Thickness and Wall Shear Stress in Common Carotid Arteries in Healthy Male Subjects1996 · 308 citations
  4. 4Anatomic correlates of aortic pulse wave velocity and carotid artery elasticity during atherosclerosis progression and regression in monkeys.1991 · 215 citations
  5. 5Ultrasound-determined intima-media thickness and atherosclerosis. Direct and indirect validation.1994 · 239 citations