Why the study?
Does preoperative ACE inhibitor or ARB therapy increase the vasoactive infusion score or incidence of hypotension in pediatric patients undergoing cardiopulmonary bypass?
Population
Pediatric patients younger than 18 years who underwent cardiopulmonary bypass between March 1, 2010, and…
Comparison
Preoperative angiotensin-converting enzyme… vs No preoperative ACE inhibitor or ARB therapy
Design
Cohort
Follow-up
Up to 90 minutes after cessation of cardiopulmonary bypass
Authors
Loading...
No significant rise in post-CPB vasoactive scores with preoperative ACEi/ARB in this pediatric cohort; leaves open questions for larger prospective studies.
Does preoperative ACE inhibitor or ARB therapy increase the vasoactive infusion score or incidence of hypotension in pediatric patients undergoing cardiopulmonary bypass?
Preoperative use of ACE inhibitors or ARBs in pediatric patients undergoing cardiac surgery does not significantly increase the incidence of hypotension or vasoconstrictor requirements after cardiopulmonary bypass.
Ajuba-Iwuji et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: