Debate: Centering Is Important

Since the first meetings dedicated to intracoronary radiation for restenosis prevention, the question of centering has been the subject of many debates. Today, more animal and clinical data are available, and some very preliminary conclusions can be drawn. From the radiation dosimetry standpoint, by allowing precise dose prescription, centering will allow the therapeutic window to be defined with greater accuracy. Moreover, because centering should lead to a lower dose to the arterial wall and a smaller irradiated volume compared with uncentered systems, centering could result in a reduction of radiation‐induced complications.