Population
cultured vascular smooth muscle cells (SMCs)
Design
Preclinical
Authors
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Suggests TFPI may limit vascular remodeling beyond anticoagulation; hypothesis-generating for restenosis models.
TFPI reduces TF/FVIIa-induced smooth muscle cell migration, suggesting a potential role in preventing vascular remodeling in addition to its antithrombotic effects.
Sato et al. (1997) studied this question.
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