Why the study?
What is the dose-response relationship of enteric coated aspirin on platelet aggregation and thromboxane formation in human volunteers?
What is the dose-response relationship of enteric coated aspirin on platelet aggregation and thromboxane formation in human volunteers?
Different doses of aspirin are required to inhibit platelet aggregation and thromboxane formation depending on the stimulus, suggesting complex dose-response dynamics.
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Stimulus-specific aspirin dosing for platelet inhibition warrants caution in assuming uniform effects; leaves open optimal regimens for consistent thromboxane suppression.
Herd et al. (1987) studied this question.
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