Why the study?
Does progressive reduction of preload affect left and right ventricular myocardial velocities measured by Doppler tissue echocardiography in healthy subjects?
Does progressive reduction of preload affect left and right ventricular myocardial velocities measured by Doppler tissue echocardiography in healthy subjects?
Myocardial E', A', and S' velocities are significantly affected by preload in healthy subjects, but the E'/A' ratio remains relatively load-independent, supporting its use as an index of diastolic function.
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Supports E'/A' ratio as relatively load-independent diastolic index in healthy subjects; leaves open validation in cardiovascular disease.
Pelà et al. (2003) studied this question.
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