April 1, 2018Journal of Atrial Fibrillation

Prospective Evaluation of Lesion Index-Guided Pulmonary Vein Isolation Technique in Patients with Paroxysmal Atrial Fibrillation: 1-year Follow-Up.

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Why the study?

Does Lesion Index (LSI)-guided pulmonary vein isolation improve AF-free survival in patients with paroxysmal atrial fibrillation compared to a non-contact force guided approach?

Population

60 consecutive patients with paroxysmal atrial fibrillation undergoing pulmonary vein isolation, mean age…

Comparison

Lesion Index-guided pulmonary vein isolation… vs Non-contact force guided pulmonary vein…

Design

Cohort

Follow-up

17±6 months

Authors

LMLuca De MattiaCa' Foncello Hospital

Discussion

Member takes

Implication

LSI-guided PVI was associated with improved outcomes in PAF; leaves open whether randomized trials should confirm superiority over standard CF guidance.

Structured PICO

Does Lesion Index (LSI)-guided pulmonary vein isolation improve AF-free survival in patients with paroxysmal atrial fibrillation compared to a non-contact force guided approach?

Population

60 consecutive patients with paroxysmal atrial fibrillation (PAF) undergoing pulmonary vein isolation (PVI), mean age 60.0, 63.3% male. 28 prospectively enrolled in LSI-guided group and 32 retrospectively collected in non-CF guided group.

Intervention

Lesion Index (LSI)-guided pulmonary vein isolation using a contact force sensing catheter. Target LSI 5.5-6 in anterior and septal portions, 5-5.5 elsewhere.

Comparator

Non-contact force (NCF) guided pulmonary vein isolation approach (retrospective historical cohort).

Outcome

AF-free survival rate at follow-up (mean 17±6 months)hard clinical

LSI-guided pulmonary vein isolation significantly improves 1-year AF-free survival compared to a non-contact force guided approach in patients with paroxysmal atrial fibrillation, without increasing complications.

Limitations

Small study sample does not allow to draw definite conclusions about the safety of an LSI-guided PVI approach.

Cite This Study

Luca De Mattia (2018) studied this question.

synapsesocial.com/papers/6a7289fc26a7f98052de58e2 https://doi.org/10.4022/jafib.1858

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Implication

LSI-guided PVI was associated with improved outcomes in PAF; leaves open whether randomized trials should confirm superiority over standard CF guidance.

Prospective Evaluation of Lesion Index-Guided Pulmonary Vein Isolation Technique in Patients with Paroxysmal Atrial Fibrillation: 1-year Follow-Up.

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Prospective Evaluation of Lesion Index-Guided Pulmonary Vein Isolation Technique in Patients with Paroxysmal Atrial Fibrillation: 1-year Follow-Up.

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

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Also Consider