Why the study?
Does the chromogenic factor X assay accurately predict a therapeutic INR in hospitalized patients transitioning from argatroban to warfarin?
Population
62 hospitalized patients with indications for anticoagulation transitioning from argatroban to warfarin
Design
Cohort
Authors
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May support chromogenic factor X monitoring during argatroban-to-warfarin transitions; hypothesis-generating and requires prospective validation.
Does the chromogenic factor X assay accurately predict a therapeutic INR in hospitalized patients transitioning from argatroban to warfarin?
A chromogenic factor X level of 45% or less is a highly sensitive and accurate predictor of a therapeutic INR when transitioning patients from argatroban to warfarin.
Arpino et al. (2005) studied this question.
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