What question did this study set out to answer?

To evaluate the midterm surgical performance, safety, and reintervention rates of decellularized equine pericardium patches across various congenital heart defect repairs in pediatric patients.

November 7, 2022Interdisciplinary CardioVascular and Thoracic SurgeryOpen Access

Midterm performance of decellularized equine pericardium in congenital heart surgery

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Authors

VWViktoria WeixlerHospital for Sick Children KKKira KuschnerusDeutsches Herzzentrum der Charité OROlga RomanchenkoHumboldt-Universität zu Berlin

Discussion

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Implication

Retrospective study reports acceptable midterm outcomes for decellularized equine pericardium patches in pediatric heart defect repairs, highlighting frequent reinterventions in pulmonary arteries.

Key Points

To evaluate the midterm surgical performance, safety, and reintervention rates of decellularized equine pericardium patches across various congenital heart defect repairs in pediatric patients.
Retrospective review of 201 pediatric patients (median age 2.5 years, IQR 0.6–6.5) undergoing 207 surgical procedures with 314 patch implant locations between 2016 and 2020.
Assessed patch handling, hemostasis, and early complications, followed by midterm performance analysis in 132 patients (200 locations) with at least 12 months of follow-up (median 29.7 months).
Early 30-day mortality was 6.5%, early reinterventions occurred in 8.9% of implant locations (n=28), and patch-related bleeding occurred in 1.0% (n=3).
During median follow-up, 53 patch-related reoperations or catheter reinterventions occurred (26.5%), with 88.7% (47/53) situated in the pulmonary artery position.
Freedom from patch-related reoperation or catheter reintervention per location was 91.5% (95% CI: 86.7%–94.6%) at 12 months and 85.2% (95% CI: 78.9%–89.6%) at 24 months.

Cite This Study

Weixler et al. (2022) studied this question.

synapsesocial.com/papers/6a7290b8febe604dd70aab5a https://doi.org/10.1093/icvts/ivac269

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November 7, 2022Interdisciplinary CardioVascular and Thoracic SurgeryOpen Access

Midterm performance of decellularized equine pericardium in congenital heart surgery

View Full Paper

Ask AI

Bookmark

Authors

VWViktoria WeixlerHospital for Sick Children KKKira KuschnerusDeutsches Herzzentrum der Charité OROlga RomanchenkoHumboldt-Universität zu Berlin

Discussion

Member takes

Implication

Retrospective study reports acceptable midterm outcomes for decellularized equine pericardium patches in pediatric heart defect repairs, highlighting frequent reinterventions in pulmonary arteries.

Key Points

To evaluate the midterm surgical performance, safety, and reintervention rates of decellularized equine pericardium patches across various congenital heart defect repairs in pediatric patients.
Retrospective review of 201 pediatric patients (median age 2.5 years, IQR 0.6–6.5) undergoing 207 surgical procedures with 314 patch implant locations between 2016 and 2020.
Assessed patch handling, hemostasis, and early complications, followed by midterm performance analysis in 132 patients (200 locations) with at least 12 months of follow-up (median 29.7 months).
Early 30-day mortality was 6.5%, early reinterventions occurred in 8.9% of implant locations (n=28), and patch-related bleeding occurred in 1.0% (n=3).
During median follow-up, 53 patch-related reoperations or catheter reinterventions occurred (26.5%), with 88.7% (47/53) situated in the pulmonary artery position.
Freedom from patch-related reoperation or catheter reintervention per location was 91.5% (95% CI: 86.7%–94.6%) at 12 months and 85.2% (95% CI: 78.9%–89.6%) at 24 months.

Cite This Study

Weixler et al. (2022) studied this question.

synapsesocial.com/papers/6a7290b8febe604dd70aab5a https://doi.org/10.1093/icvts/ivac269

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