Why the study?
Endothelin-1 contributes to endothelial dysfunction and inflammation in CAD, and diabetes exacerbates vascular endothelial damage, motivating evaluation of ET-1 and its relation to CAD severity in diabetic patients.
Does plasma endothelin-1 (ET-1) level correlate with the severity of coronary artery disease in diabetic patients?
Comparison
Diabetic CAD patients vs nondiabetic CAD patients vs normal coronary controls
Design
Case-control study
Authors
Loading...
Plasma ET-1 may stratify risk in diabetic CAD patients; leaves open incremental prognostic utility beyond standard markers.
Does plasma endothelin-1 (ET-1) level correlate with the severity of coronary artery disease in diabetic patients?
Plasma endothelin-1 levels are significantly elevated in diabetic patients with coronary artery disease and correlate positively with angiographic disease severity.
Eldegwi et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: