Why the study?
Are plasma endothelin-1 levels elevated in non-insulin-dependent diabetes mellitus patients with macrovascular disease compared to those with coronary artery disease alone or healthy controls?
Population
50 subjects including 20 patients with non-insulin-dependent diabetes mellitus and coronary artery disease…
Design
Cross-sectional
Authors
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Plasma ET-1 levels not elevated in NIDDM+CAD; leaves open its biomarker role in diabetic macrovascular disease.
Are plasma endothelin-1 levels elevated in non-insulin-dependent diabetes mellitus patients with macrovascular disease compared to those with coronary artery disease alone or healthy controls?
Plasma endothelin-1 concentrations are not significantly elevated in NIDDM patients with macrovascular disease compared to CAD patients or healthy controls.
Güvener et al. (1997) studied this question.
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