Why the study?
Are plasma endothelin-1 levels elevated in patients with non-insulin-dependent diabetes mellitus with or without angiopathy compared to normal subjects?
Population
46 subjects, comprising 25 patients with non-insulin-dependent diabetes mellitus and 21 normal subjects.
Design
Cross-sectional
Authors
Loading...
ET-1 levels not elevated in diabetes with or without angiopathy; challenges in vitro data and leaves pathogenic role open.
Are plasma endothelin-1 levels elevated in patients with non-insulin-dependent diabetes mellitus with or without angiopathy compared to normal subjects?
Circulating endothelin-1 levels do not appear to be elevated in patients with non-insulin-dependent diabetes mellitus, regardless of the presence of angiopathy.
Kanno et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: