Why the study?
Are plasma ET-1 levels elevated in NIDDM patients with or without complications compared to healthy subjects?
Population
44 NIDDM patients and 30 normotensive healthy individuals
Comparison
Measurement of plasma endothelin 1 (ET-1) levels vs Normotensive healthy (nondiabetic) individuals
Design
Cross-sectional
Authors
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Does not support ET-1 as a marker for NIDDM or angiopathy; leaves open its role in diabetic vascular disease.
Are plasma ET-1 levels elevated in NIDDM patients with or without complications compared to healthy subjects?
Plasma ET-1 levels do not appear to be elevated in NIDDM patients or act as a marker for diabetic complications such as angiopathy.
Bertello et al. (1994) studied this question.
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