Why the study?
Does nifedipine reduce blood pressure and prevent cardiac hypertrophy in hypertensive rat models?
Does nifedipine reduce blood pressure and prevent cardiac hypertrophy in hypertensive rat models?
Nifedipine, unlike the vasodilator minoxidil, reduces blood pressure while simultaneously preventing or regressing hypertensive cardiac hypertrophy in rat models.
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Nifedipine may avoid hypertrophy promotion unlike minoxidil in hypertensive rat models; hypothesis-generating and leaves open human translation.
Kazda et al. (1982) studied this question.
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