Why the study?
Does aspirin reduce platelet lifespan and induce apoptosis in murine models and human platelets in vitro?
Does aspirin reduce platelet lifespan and induce apoptosis in murine models and human platelets in vitro?
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Aspirin reduces platelet lifespan and promotes platelet apoptosis via proteasomal inhibition at anti-inflammatory doses, suggesting a need to re-evaluate its dosage regimens.
Nayak et al. (2014) studied this question.
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