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January 1, 2013Evidence-based Complementary and Alternative MedicineOpen Access

The Effects of Xuefu Zhuyu and Shengmai on the Evolution of Syndromes and Inflammatory Markers in Patients with Unstable Angina Pectoris after Percutaneous Coronary Intervention: A Randomised Controlled Clinical Trial

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Why the study?

Do Xuefu Zhuyu and Shengmai capsules improve traditional syndromes and reduce inflammatory markers in patients with unstable angina pectoris after PCI compared to placebo?

Population

90 patients with unstable angina pectoris (UAP) after percutaneous coronary intervention (PCI)

Comparison

Xuefu Zhuyu capsule or Shengmai capsule vs Placebo

Design

RCT, Randomly and equally assigned to three groups

Follow-up

12 weeks

Authors

JWJie WangXYXiaochen YangFCFu-yong Chu

Discussion

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Overview

Supports adjunctive XFZY and SM after PCI to stabilize TCM syndromes and reduce inflammation; extends evidence for integrative approaches in unstable angina.

Structured PICO

Do Xuefu Zhuyu and Shengmai capsules improve traditional syndromes and reduce inflammatory markers in patients with unstable angina pectoris after PCI compared to placebo?

P
Population
90 patients with unstable angina pectoris (UAP) after percutaneous coronary intervention (PCI)
I
Intervention
Xuefu Zhuyu capsule (XFZY) or Shengmai capsule (SM)
C
Comparator
Placebo
O
Outcome
Evolution of six syndrome factors (Qi deficiency, yin deficiency, yang deficiency, blood stasis, phlegm, and Qi stagnation) and 4 inflammatory markers (Hs-CRP, ET-1, MMP-9, and Hcy) at week 0, 1, 4, and 12surrogate

Xuefu Zhuyu and Shengmai capsules may modulate traditional Chinese medicine syndromes and reduce inflammatory markers in patients with unstable angina after PCI.

Cite This Study

Wang et al. (2013) studied this question.

synapsesocial.com/papers/6a72b745439bab0cabc3e8f2https://doi.org/10.1155/2013/896467
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