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November 1, 2023International Journal of Geriatric Psychiatry

Association of multimorbidity patterns with motoric cognitive risk syndrome among older adults: Evidence from a China longitudinal study

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Authors

FXFeiyang XiongYWYizhong WangJZJun Zhu

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Overview

Longitudinal study finds that multimorbidity—especially cardiovascular conditions—increases motoric cognitive risk syndrome in older adults, highlighting targets for early prevention.

Key Points

  • To evaluate the longitudinal associations between multimorbidity, specific disease patterns, and the incidence of motoric cognitive risk syndrome in older adults.
  • Analyzed longitudinal data across three waves (2011, 2013, and 2015) of the China Health and Retirement Longitudinal Study among 4,923 adults aged 60 and older who were free of motoric cognitive risk syndrome at baseline.
  • Classified multimorbidity patterns using latent class analysis and estimated hazard ratios for motoric cognitive risk syndrome onset using multivariable-adjusted Cox proportional hazards models.
  • Baseline multimorbidity significantly increased the risk of developing motoric cognitive risk syndrome (HR = 1.33, 95% CI = 1.06–1.68), with risk increasing alongside the number of co-occurring conditions (HR = 1.10, 95% CI = 1.02–1.19).
  • Compared with a relatively healthy pattern, the cardiovascular multimorbidity pattern elevated the risk of motoric cognitive risk syndrome by 57% (HR = 1.57, 95% CI = 1.16–2.13), while the respiratory pattern did not show a statistically significant association (HR = 1.31, 95% CI = 0.91–1.92).

Cite This Study

Xiong et al. (2023) studied this question.

synapsesocial.com/papers/6a72be8a31a3df82432a3ce7https://doi.org/10.1002/gps.6021
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