Why the study?
Does the global withdrawal of OPV2 reduce the detection of Sabin-2 poliovirus and VDPV2?
Does the global withdrawal of OPV2 reduce the detection of Sabin-2 poliovirus and VDPV2?
Global withdrawal of OPV2 led to a rapid decline in Sabin-2 poliovirus prevalence, though outbreaks of VDPV2 occurred in areas with low routine immunization coverage.
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Sustained high immunity needed to prevent post-withdrawal VDPV2 outbreaks; leaves open full eradication feasibility in low-coverage settings.
Blake et al. (2018) studied this question.
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