Effects of physical activity on endothelial progenitor cells (EPCs)
Why the study?
Does physical activity improve endothelial function and EPC levels in healthy subjects and patients with cardiovascular disease?
Population
Healthy subjects and patients with cardiovascular disease
Design
Review
Authors
Discussion
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Member takes
Implication
May support EPC-mediated vascular benefits from exercise in CVD; hypothesis-generating pending RCTs on clinical outcomes.
Structured PICO
Does physical activity improve endothelial function and EPC levels in healthy subjects and patients with cardiovascular disease?
P
Population
Healthy subjects and patients with cardiovascular disease (including coronary artery disease, heart failure, and peripheral artery disease)
I
Intervention
Physical activity / exercise
O
Outcome
Endothelial function and endothelial progenitor cells (EPCs) levels and activitysurrogate
Physical activity improves endothelial function and increases circulating endothelial progenitor cells, providing a mechanism for its therapeutic role in cardiovascular disease.
Cite This Study
Biase et al. (2014) studied this question.